a-actinin Antibody from MYBIOSOURCE INC.

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Antigenic Specificitya-actinin
Clone[1D4]
Host SpeciesMouse
Reactive Specieshuman, mouse, rat
IsotypeIgG
FormatProtein A purified
Size0.02 mL, 0.06 mL, 0.12 mL
Concentration1mg/mL
ApplicationsImmunohistochemistry (IHC) Paraffin (IHC-p)
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DescriptionAlpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Thre
ImmunogenImmunogen: Recombinant Protein of a-actinin of ACTN1 Buffer: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4 Conjugation: Unconjugated
Other Names[alpha-actinin-1 isoform b; Alpha-actinin-1; alpha-actinin-1; actinin alpha 1; Alpha-actinin cytoskeletal isoform; F-actin cross-linking protein; Non-muscle alpha-actinin-1]
Gene, Accession #[ACTN1], Gene ID: 87, NCBI: NP_001093.1, UniProt: P12814
Catalog #MBS2548904
Price$110, $150, $225
Order / More Infoa-actinin Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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