SMYD2 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificitySMYD2
Clonemonoclonal
Host SpeciesMouse
Reactive Specieshuman, mouse
IsotypeIgG2b
Formatunconjugated
Size0.1 mg
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionThis antibody detects endogenous levels of SMYD2 and does not cross-react with related proteins. UniPort Summary Function: Protein-lysine N-methyltransferase that methylates both histones and non-histone proteins. Specifically methylates histone H3 ?Lys-4? (H3K4me) and dimethylates histone H3 ?Lys-36? (H3K36me2). Has also methyltransferase activity toward non-histone proteins such as p53/TP53 and RB1. Monomethylates ?Lys-370? of p53/TP53, leading to decreased DNA-binding activity and subsequent transcriptional regulation activity of p53/TP53. Monomethylates ?Lys-860? of RB1/RB. Entrez Summary: SET domain-containing proteins, such as SMYD2, catalyze lysine methylation (Brown et al., 2006 [PubMed 16805913]).[supplied by OMIM, Nov 2008]
ImmunogenImmunogen: Purified recombinant human SMYD2 protein fragments expressed in E Coli. Cellular Localization: Cytoplasm Cytosol; Nucleus
Other Names[HSKM-B; Histone methyltransferase SMYD2; EC=2.1.1.43; Lysine N-methyltransferase 3C; SET and MYND domain-containing protein 2], [KMT3C; HSKM-B; ZMYND14]
Gene, Accession #[SMYD2], Gene ID: 56950, NCBI: NP_064582.2, UniProt: Q9NRG4
Catalog #MBS857789
Price$300
Order / More InfoSMYD2 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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