bcl-2 Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | bcl-2 |
| Clone | [BCL2/A4] |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1/k |
| Format | unconjugated |
| Size | 5 Control Slides, 0.1 mL (Concentrate), 3 ml (Prediluted) |
| Concentration | n/a |
| Applications | n/a |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | bcl-2 is an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of bcl-2, such as in the case of translocation of bcl-2 to Ig heavy-chain loci, is thought to be the cause of Follicular Lymphoma. Anti-bcl-2 has shown consistent negative reaction on reactive germinal centers and positive staining of neoplastic follicles in Follicular Lymphoma. Consequently, this antibody is valuable when distinguishing between reactive and neoplastic follicular proliferation in lymph node biopsies. This antibody may also be used in distinguishing between those Follicular Lymphomas that express bcl-2 protein and the small number in which the neoplastic cells are bcl-2-negative |
| Immunogen | n/a |
| Other Names | [BCL-2; Apoptosis regulator Bcl-2; apoptosis regulator Bcl-2; Bcl2-like protein; B-cell leukemia/lymphoma 2; B cell lymphoma 2 associated oncogene; B-cell CLL/lymphoma 2], [Bcl2; Bcl2; Bcl-2; Bcl-2] |
| Gene, Accession # | [bcl-2], Gene ID: 24224, NCBI: AAA77687.1, UniProt: P49950 |
| Catalog # | MBS370007 |
| Price | $130, $165, $165 |
| Order / More Info | bcl-2 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
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