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Antigenic Specificity | ALS2 - middle region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | cow, dog, guinea pig, horse, human, mouse, porcine, rabbit, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This is a rabbit polyclonal antibody against ALS2. It was validated on Western Blot using a cell lysate as a positive control.Target Description: The protein encoded by this gene contains an ATS1/RCC1-like domain, a RhoGEF domain, and a vacuolar protein sorting 9 (VPS9) domain, all of which are guanine-nucleotide exchange factors that activate members of the Ras superfamily of GTPases. The protein functions as a guanine nucleotide exchange factor for the small GTPase RAB5. The protein localizes with RAB5 on early endosomal compartments, and functions as a modulator for endosomal dynamics. Mutations in this gene result in several forms of juvenile lateral sclerosis and infantile-onset ascending spastic paralysis. Multiple transcript |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ALS2 |
Other Names | [alsin isoform 1; Alsin; alsin; alsin Rho guanine nucleotide exchange factor ALS2; Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 6 protein; Amyotrophic lateral sclerosis 2 protein] |
Gene, Accession # | [ALS2], Gene ID: 57679, NCBI: NP_065970, UniProt: Q96Q42 |
Catalog # | MBS3213382 |
Price | $335 |
Order / More Info | ALS2 - middle region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |