Mouse T-cell Immunoglobulin Mucin-3 (TIM-3) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Mouse T-cell Immunoglobulin Mucin-3 (TIM-3) |
| Clone | [6F46] |
| Host Species | Rat |
| Reactive Species | mouse |
| Isotype | IgG2 |
| Format | Protein A purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This antibody detects mouse of TIM-3 in Western blotting. This antibody does not cross-react with mouse TIM-1 and TIM-2. T cell immunoglobulin mucin-3 (TIM-3) is a member of the T-cell Immunoglobulin- and Mucin-domain-containing family of type I membrane glycoproteins that regulate autoimmune and allergic disease. TIM-3 is selectively expressed on Th1 cells and interacts with galectin-9. It negatively regulates Th1 responses and affects macrophage activation. The 280 aa mature human TIM-3 contains a V-type Ig-like domain that shows multiple polymorphisms, followed by a mucin-like domain in the 171 aa extracellular region, which shares 60% amino acid identity with mouse TIM-3 ECD. One splice variant of TIM-3 is truncated within the mucin dom |
| Immunogen | Antibody Generation: This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a rat immunized with purified mouse recombinant TIM-3. The IgG2 fraction of the culture supernatant was purified by Protein A/G affinity chromatography. |
| Other Names | [mouse TIM-3 [T-cell Immunoglobulin Mucin-3] (#6F46)], [Havcr2; Havcr2; Tim3; TIM-3; Timd3; Tim3; Timd3; HAVcr-2; TIMD-3; TIM-3] |
| Gene, Accession # | [TIM-3], Gene ID: 171285, NCBI: NP_599011.2, UniProt: Q8VIM0 |
| Catalog # | MBS690232 |
| Price | $490 |
| Order / More Info | Mouse T-cell Immunoglobulin Mucin-3 (TIM-3) Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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