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Antigenic Specificity | Phospho-PKC zeta (Thr410) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemisty (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-PKC zeta (Thr410) antibody detects endogenous levels of PKC zeta only when phosphorylated at Threonine 410. Description: Protein kinase C (PKC) zeta is a member of the PKC family of serine/threonine kinases which are involved in a variety of cellular processes such as proliferation, differentiation and secretion.Function: Calcium-and diacylglycerol-independent serine/threonine-protein kinase that functions in phosphatidylinositol 3-kinase (PI3K) pathway and mitogen-activated protein (MAP) kinase cascade, and is involved in NF-kappa-B activation, mitogenic signaling, cell proliferation, cell polarity, inflammatory response and maintenance of long-term potentiation (LTP). Upon lipopolysaccharide (LPS) treatment in mac |
Immunogen | Immunogen: A synthesized peptide derived from human PKC zeta around the phosphorylation site of Threonine 410 Subcellular Location: Cytoplasm. Endosome. Cell Junction. In the retina, localizes in the terminals of the rod bipolar cells (By similarity). Associates with endosomes. Presence of KRIT1, CDH5 and RAP1B is required for its localization to the cell junction. Tissue Specificity: Expressed in brain, and to a lesser extent in lung, kidney and testis. Predicted Cross Reactivity: Pig, Zebrafis |
Other Names | [14-3-3-zetaisoform; AI098070; aPKCzeta; C80388; EC 2.7.11.13; KPCZ_HUMAN; nPKC zeta; nPKC-zeta; OTTHUMP00000001368; OTTHUMP00000044160; PKC 2; PKC ZETA; PKC2; Pkcz; PKCZETA; PKM-zeta, included; PRKCZ; Protein kinase C zeta; Protein kinase C zeta form; Protein kinase C zeta type; r14-3-3; R74924; zetaPKC] |
Gene, Accession # | [PRKCZ], Gene ID: 5590, NCBI: NP_001028753.1, UniProt: Q05513 |
Catalog # | MBS9601173 |
Price | $240, $280 |
Order / More Info | Phospho-PKC zeta (Thr410) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |