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Antigenic Specificity | gamma-Catenin (Tyr-550), phospho-specific |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, rat, mouse |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | ELISA, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody was cross-adsorbed to both phospho-tyrosine coupled to agarose and to dephosphorylated gamma-Catenin (Tyr-550) peptide before affinity purification using phospho-gamma-Catenin (Tyr-550) peptide (without carrier). The antibody detects an 84kDa* protein corresponding to the molecular mass of gamma-Catenin on SDS-PAGE immunoblots of A431 and Hct116 src transformed cells treated with pervanadate (1 mM for 30 min), but not in control cells. Plakoglobin (gamma-catenin) is a catenin family member that was identified as a component of desmosomes. It associates with various cell adhesion related proteins, such as desmoglein and cadherins. gamma-Catenin has high homology to beta-catenin and, like beta-catenin, it can associate with the |
Immunogen | Immunogen: Phospho-gamma-Catenin (Tyr-550) synthetic peptide (coupled to KLH) corresponding to amino acid residues around tyrosine 550 of human gamma-Catenin. This peptide sequence is highly conserved in rat and mouse gamma-Catenin. |
Other Names | n/a |
Gene, Accession # | n/a |
Catalog # | MBS472026 |
Price | $385 |
Order / More Info | gamma-Catenin (Tyr-550), phospho-specific Antibody from MYBIOSOURCE INC. |
Product Specific References | • McCrea, P.D., et al. (1991) Science 254:1359.• Miravet, S. et al. (2003) Mol. Cell. Biol. 23(20) :7391. |