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Antigenic Specificity | RIPK1 / RIP |
Clone | [2G3] |
Host Species | Mouse |
Reactive Species | dog, human |
Isotype | IgG2a |
Format | Protein A purified |
Size | 0.05 mL |
Concentration | 1 mg/ml |
Applications | Immunohistochemistry (IHC) Paraffin, Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Human RIP. RIPK1 Antibody, Cell death protein RIP Antibody, Receptor interacting protein Antibody, RIP1 Antibody, RIP Antibody, RIP-1 Antibody, Protein kinase rip Antibody, Receptor-interacting protein 1 Antibody, Rinp Antibody Description: Serine-threonine kinase which transduces inflammatory and cell-death signals (programmed necrosis) following death receptors ligation, activation of pathogen recognition receptors (PRRs), and DNA damage. Upon activation of TNFR1 by the TNF-alpha family cytokines, TRADD and TRAF2 are recruited to the receptor. Phosphorylates DAB2IP at 'ser-728' in a TNF-alpha-dependent manner, and thereby activates the MAP3K5-JNK apoptotic cascade. |
Immunogen | Immunogen Description: Human recombinant protein fragment corresponding to amino acids 133-422 of human RIPK1(NP_003795) produced in E Coli. Immunogen Type: Recombinant protein |
Other Names | [Mouse [clone 2G3] (IgG2a) to Human RIPK1 / RIP; Human RIPK1 / RIP; Cell death protein RIP; Receptor interacting protein; RIP1; RIP-1; Protein kinase rip; Receptor-interacting protein 1; Rinp], [RIPK1; RIPK1; RIP; RIP1; RIP-1; RIP; RIP1; RIP-1] |
Gene, Accession # | [RIPK1 / RIP], Gene ID: 8737, NCBI: NP_003795.2, UniProt: Q13546 |
Catalog # | MBS249256 |
Price | $530 |
Order / More Info | RIPK1 / RIP Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |