SNAP25 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificitySNAP25
Clonemonoclonal
Host SpeciesMouse
Reactive Specieshuman, mouse, rat
IsotypeIgG2b
Formatcaprylic acid ammonium sulfate precipitate
Size0.06 mL, 0.12 mL, 0.2 mL
Concentration1mg/mL
ApplicationsELISA (EIA), Immunofluorescence (IF), Western Blot (WB)
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DescriptionThe synaptosomal associated protein of 25 kD (SNAP-25) was first identified as a major synaptic protein by Wilson and colleagues. The protein interacts with syntaxin and synaptobrevin through its N-terminal and C-terminal -helical domains. Its palmitoylation domain is located in the middle of the molecule that contains four cysteine residues. Mutation of the cysteines abolishes palmitoylation and membrane binding. Several elegant studies using synaptosome preparations and permeabilized PC12 cells have suggested that SNAP-25 may act in the late post-docking steps of exocytosis. By limited proteolysis and in vitro binding assay, it is proposed that the two helix domains act independently and contribute equally to form the SNARE complex with s
ImmunogenImmunogen: SNAP25 fusion protein ag6695
Other Names[bA416N4.2; dJ1068F16.2; FLJ23079; RIC 4; RIC4; SEC9; SNAP; SNAP 25; SNAP25; SUP; Super protein]
Gene, Accession #[SNAP25], Gene ID: 6616, NCBI: NP_001309831.1, UniProt: P60880
Catalog #MBS2540238
Price$220, $290, $435
Order / More InfoSNAP25 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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