Edit |   |
---|---|
Antigenic Specificity | SNAP25 |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human, mouse, rat |
Isotype | IgG2b |
Format | caprylic acid ammonium sulfate precipitate |
Size | 0.06 mL, 0.12 mL, 0.2 mL |
Concentration | 1mg/mL |
Applications | ELISA (EIA), Immunofluorescence (IF), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The synaptosomal associated protein of 25 kD (SNAP-25) was first identified as a major synaptic protein by Wilson and colleagues. The protein interacts with syntaxin and synaptobrevin through its N-terminal and C-terminal -helical domains. Its palmitoylation domain is located in the middle of the molecule that contains four cysteine residues. Mutation of the cysteines abolishes palmitoylation and membrane binding. Several elegant studies using synaptosome preparations and permeabilized PC12 cells have suggested that SNAP-25 may act in the late post-docking steps of exocytosis. By limited proteolysis and in vitro binding assay, it is proposed that the two helix domains act independently and contribute equally to form the SNARE complex with s |
Immunogen | Immunogen: SNAP25 fusion protein ag6695 |
Other Names | [bA416N4.2; dJ1068F16.2; FLJ23079; RIC 4; RIC4; SEC9; SNAP; SNAP 25; SNAP25; SUP; Super protein] |
Gene, Accession # | [SNAP25], Gene ID: 6616, NCBI: NP_001309831.1, UniProt: P60880 |
Catalog # | MBS2540238 |
Price | $220, $290, $435 |
Order / More Info | SNAP25 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |