Human CD74 Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-Human CD74 antibody, protein, ELISA kits.
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|---|---|
| Antigenic Specificity | Human CD74 |
| Clone | [4ALN2] |
| Host Species | Mouse |
| Reactive Species | n/a |
| Isotype | IgG1 |
| Format | fluorescein (FITC) conjugate |
| Size | 50 tests, 100 tests |
| Concentration | n/a |
| Applications | Flow Cytometry (FC/FACS), Immunofluorescence (IF) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The 4ALN2 monoclonal antibody recognizes human CD74, also known as the MHC Class II-associated invariant chain. A 33-43 kDa nonpolymorphic type II membrane protein, CD74 is highly expressed on B cells and subsets of activated T cells, Langerhans cells, dendritic cells, and epithelial cells. Monocytes and macrophages also express CD74, but at lower levels. CD74 acts as a chaperone of MHC Class II (HLA-DR) proteins, promoting their translocation from the ER to endocytic compartments during antigen presentation. Activation of NFkappaB and ERK has been shown following CD74 interaction with CD44 and binding to the proinflammatory cytokine macrophage migration-inhibitory factor (MIF). CD74 also plays a role in the maturation of follicular B-cells |
| Immunogen | n/a |
| Other Names | [CD74 antigen; CD74 antigen] |
| Gene, Accession # | [CD74], Gene ID: 396660, NCBI: NP_998939.1 |
| Catalog # | MBS8500247 |
| Price | $215, $280 |
| Order / More Info | Human CD74 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. You CX et al., (2012) Oncoimmunology 1(6):847-855. 2. Gibbons RM et al., (2012) Oncoimmunology 1(7):1061-1073. 3. Garufi A et al., (2012) PLoS One 7(11):e48342. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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