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Antigenic Specificity | TORC2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Rabbit IgG polyclonal antibody for CREB-regulated transcription coactivator 2(CRTC2) detection. Tested with WB in Human. Background: CRTC2(CREB-Regulated Transcription Coactivator 2), also known as TORC2, is a protein that in humans is encoded by the CRTC2 gene. The International Radiation Hybrid Mapping Consortium mapped the CRTC2 gene to chromosome 1. By cotransfection of TORC2 and reporter genes in HeLa cells, Iourgenko et al.(2003) found that TORC2 potently activated expression of genes driven by the IL8 promoter or a promoter carrying multiple CRE-like sequences. Liu et al.(2008) demonstrated that a fasting-inducible switch, consisting of the histone acetyltransferase p300 and the nutrient-sensing deacetylase sirtuin-1(SIR |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human TORC2 (595-611aa QDPHTFNHQNLTHCSRH), different from the related rat sequence by three amino acids, and from the related mouse sequence by two amino acids. |
Other Names | [CREB-regulated transcription coactivator 2; CREB regulated transcription coactivator 2; CREB regulated transcription coactivator 2; CREB-regulated transcription coactivator 2; CRTC2; CRTC2_HUMAN; RP11-422P24.6; TORC-2; torc2; Transducer of CREB protein 2; Transducer of regulated cAMP response element-binding protein; Transducer of regulated cAMP response element-binding protein(CREB) 2; Transducer of regulated cAMP response element-binding protein 2; Transducer of regulated CREB protein 2], [CRTC2; CRTC2; TORC2; TORC-2; TORC2; TORC-2; Transducer of CREB protein 2] |
Gene, Accession # | [CRTC2], Gene ID: 200186, NCBI: Q53ET0.2, UniProt: Q53ET0 |
Catalog # | MBS176326 |
Price | $280 |
Order / More Info | TORC2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |