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Antigenic Specificity | Phospho-CDKN1B-T187 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene encodes a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state. Mutations in this gene are associated with multiple endocrine neoplasia type IV (MEN4). |
Immunogen | Immunogen: A phospho specific peptide corresponding to residues surrounding T187 of human p27 KIP 1. |
Other Names | [CDKN1B; CDKN4; KIP1; MEN1B; MEN4; P27KIP1; Cyclin-dependent kinase inhibitor 1B], [CDKN1B; CDKN1B; KIP1; MEN4; CDKN4; MEN1B; P27KIP1; KIP1] |
Gene, Accession # | [CDKN1B], Gene ID: 1027, NCBI: P46527.1, UniProt: P46527 |
Catalog # | MBS128516 |
Price | $235, $350, $525 |
Order / More Info | Phospho-CDKN1B-T187 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |