Phospho-ANTXR1 (Y382) Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | Phospho-ANTXR1 (Y382) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human (predicted reactivity: mouse, rat) |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.38 |
| Applications | Dot Blot (DB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This ANTXR1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y382 of human ANTXR1. ANTXR1 is a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. This protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cell |
| Immunogen | n/a |
| Other Names | [Anthrax toxin receptor 1; Tumor endothelial marker 8; ANTXR1; ATR; TEM8] |
| Gene, Accession # | [ANTXR1], Gene ID: 84168, NCBI: NP_060623.2, UniProt: Q9H6X2 |
| Catalog # | MBS9201536 |
| Price | $165, $370 |
| Order / More Info | Phospho-ANTXR1 (Y382) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Werner,E., J. Biol. Chem. 281 (32), 23227-23236 (2006) Wei,W., Cell 124 (6), 1141-1154 (2006) Rainey,G.J., Proc. Natl. Acad. Sci. U.S.A. 102 (37), 13278-13283 (2005) |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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