HEA125, Epithelium-specific Glycoprotein, Egp34, EpCAM (CD326) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | HEA125, Epithelium-specific Glycoprotein, Egp34, EpCAM (CD326) |
| Clone | polyclonal |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | n/a |
| Format | unconjugated |
| Size | 1 mL |
| Concentration | 50 ug/ml |
| Applications | Immunohistochemistry (IHC) Formalin/Paraffin, Flow Cytometry (FC/FACS) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The antibody HEA 125 reacts intensely with all carcinoma derived from the intestinal tract, stomach, pancreas, liver, lung, breast, ovary, thyroid gland, kidney, bladder, prostate and metastases thereof. Stratified squamous epithelia usually stain less intensely then adenocarcinoma. The antibody is suitable for differentiation between carcinoma an non-carcinoma. Keratinizing areas of a tumour mass usually remain unstained as sarcoma, lymphoma, melanoma and neurogenic tumours do. Epithelial cells express a number of characteristic proteins and glycoproteins like cytokeratins, epithelial membrane antigen and epithelium-specific glycoprotein Egp34 (HEA125). The monoclonal antibody HEA125 which has been derived from immunisation of mice with a |
| Immunogen | Immunogen: Living human colon carcinoma cell line HT-29 |
| Other Names | [epithelial cell adhesion molecule; Epithelial cell adhesion molecule; epithelial cell adhesion molecule; epithelial cell adhesion molecule; Adenocarcinoma-associated antigen; Cell surface glycoprotein Trop-1; Epithelial cell surface antigen; Epithelial glycoprotein; EGP; Epithelial glycoprotein 314; EGP314; hEGP314; KS 1/4 antigen; KSA; Major gastrointestinal tumor-associated protein GA733-2; Tumor-associated calcium signal transducer 1; CD_antigen: CD326], [EPCAM; EPCAM; ESA; KSA; M4S1; MK-1; DIAR5; EGP-2; EGP40; KS1/4; MIC18; TROP1; EGP314; HNPCC8; TACSTD1; GA733-2; M1S2; M4S1; MIC18; TACSTD1; TROP1; Ep-CAM; EGP; EGP314; hEGP314] |
| Gene, Accession # | [HEA125], Gene ID: 4072, NCBI: NP_002345.2, UniProt: P16422 |
| Catalog # | MBS397229 |
| Price | $415 |
| Order / More Info | HEA125, Epithelium-specific Glycoprotein, Egp34, EpCAM (CD326) Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Moldenhauer G., Momburg F., Moller P., Schwartz, and Hammerling G.J. (1987) Epithelium-specific surface glycoprotein of Mr 34,000 is a widely distributed human carcinoma marker. Br. J. Cancer 56; 714-721. 2. Momburg F., Moldenhauer G., Hammerling G.J., and Moller F. (1987) Immunohistochemical study of the expression of a Mr 34,000 human epithelium-specific surface glycoprotein in normal and malignant tissues. Cancer Research 47; 2883-2891. 3. Simon B., Podolsky, D.K., Moldenhauer G., Isselbacher K.J., Gattoni-Celli, S., and Brand S.J. (1990) Epithelial glykoprotein is a member of a family of epithelial cell surface antigens homologous to nidogen, a matrix adhesion protein. Proc. Natl., Acad. Sci. USA 87; 2755 ff. 4. Kemmner W., Moldenhauer G., Schlag P., and Brossmer R. (1992) Separation of tumor cells from a suspension of dissociated human colorectal carcionoma tissue by means of monoclonal antibody-coated magnetic beads. J. Immunol. Methods 147; 197-200. 5. Winter, M. J. et al. (2003) The epithelial cell adhesion molecule (Ep-CAM) as a morphoregulatory molecule is a tool in surgical pathology. Am. J. Pathol. 163: 2139-2148. |
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