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Antigenic Specificity | EID1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.02 mL, 0.06 mL, 0.12 mL |
Concentration | 1.6mg/mL |
Applications | ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | E1A-like inhibitor of differentiation-1 (EID-1), an acetyltransferase enzyme, binds both the retinoblastoma protein (Rb), a regulator of cell cycle and tissue specific transcription, and the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. EID-1 inhibits cellular differentiation by blocking the histone acetyltransferase activity of p300. EID-1 also acetylates both histones and non-histone proteins such as NCOA3 co-activator. By acetylating histones, EID-1 gives a specific tag for transcriptional activation. In addition to binding Rb and p300, EID-1 also binds to phosphorylated CREB protein, mediating cAMP gene regulation. EID-1 augments the activity of phosphorylated CREB and activates transcription of cAMP resp |
Immunogen | Immunogen: Recombinant protein of human EID1 |
Other Names | [CRI1; EID-1; RBP21; PTD014; C15orf3; PNAS-22; IRO45620] |
Gene, Accession # | [EID1], Gene ID: 23741, NCBI: NP_055150.1, UniProt: Q9Y6B2 |
Catalog # | MBS2528774 |
Price | $110, $150, $225 |
Order / More Info | EID1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |