Human CD273(B7-DC) Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-Human CD273(B7-DC) antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | Human CD273(B7-DC) |
| Clone | [ANC8D12] |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG2ak |
| Format | no preservative |
| Size | 0.1 mg |
| Concentration | 1.0 mg/ml |
| Applications | Flow Cytometry (FC/FACS), ELISA (EIA), Blocking |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Information: CD273 (B7-DC, PD-L2, Programmed Death Ligand 2) is a 25 kd member of the B7 family and is expressed mainly on a sub set of Dendritic cells. When engaged it has a stimulatory effect on the expressing DC, and delivers a down regulatory signal to cells expressing its counter receptor, CD279(PD-1). The interaction of CD273(B7-DC) and CD274(B7-H1) with their receptor, CD279(PD-1) is an important component of immune regulation. Antibody ANC8D12 binds to recombinant CD273 and cell surface CD273 expressed on monocyte derived Dendritic cells (moDC), and blocks binding of recombinant CD279 to CD273 in EIA and FACS. |
| Immunogen | Immunogen: Recombinant human CD273(B7-DC) |
| Other Names | n/a |
| Gene, Accession # | [CD273] |
| Catalog # | MBS666156 |
| Price | $310 |
| Order / More Info | Human CD273(B7-DC) Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1) Carreno BM, et al. (2002) Annu. Rev. Immunol. 20:29. 2) E Gianchecchi, A Fierabracci, et al. (2013) Autoimmun Rev 12(11): 1091-1100. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
Return to Antibodies