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Antigenic Specificity | VDAC2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: VDAC2 antibody detects endogenous levels of total VDAC2. Description: Forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules. The channel adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation-selective.Subunit Structure: Interacts with hexokinases.Post-translational Modifications: Ubiquitinated by PRKN during mitophagy, leading to its degradation and enhancement of mitophagy. Deubiquitinated by USP30.Similarity: Consists mainly of a membrane-spanning beta-barrel formed by 19 beta-strands. Belongs to the eukaryotic mitocho |
Immunogen | Immunogen: A synthesized peptide derived from human VDAC2 Subcellular Location: Mitochondrion Outer Membrane Tissue Specificity: Expressed in all tissues examined. Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep, Rabbit, Dog Similarity: Pig (89%), Bovine (89%), Horse (89%), Sheep (89%), Rabbit (89%), Dog (89%) |
Other Names | [B-36 vdac; FLJ23841; hVDAC2; OTTHUMP00000019878; OTTHUMP00000019879; OTTHUMP00000019880; Outer mitochondrial membrane protein porin 2; POR; Porin-2; VDAC 2; VDAC-2; VDAC2; VDAC2_HUMAN; Vdac6; Voltage dependent anion channel 2; Voltage dependent anion selective channel protein 2; Voltage-dependent anion-selective channel protein 2] |
Gene, Accession # | [VDAC2], Gene ID: 7417, NCBI: NP_001171712.1, UniProt: P45880 |
Catalog # | MBS9601569 |
Price | $240, $280 |
Order / More Info | VDAC2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |