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Antigenic Specificity | Osteopontin |
Clone | polyclonal |
Host Species | n/a |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunocytochemistry (ICC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody is produced by immunizing rabbits with a synthetic peptide (KLH-coupled) corresponding to human Osteopontin. Osteopontin is an extracellular matrix cell adhesion protein which is abundant in bone and synthesized by preosteoblasts, osteoblasts and osteoclastic cells that are localized in the mineralized phase of bone matrix. Osteopontin probably exists in tissue-specific isoforms that may correspond to particular cellular functions. Acts as a cytokine it involved in enhancing production of interferon-gamma and interleukin-12 and reducing production of interleukin-10 and is essential in the pathway that leads to type I immunity. |
Immunogen | n/a |
Other Names | [osteopontin isoform OPN-b; Osteopontin; osteopontin; secreted phosphoprotein 1; Bone sialoprotein 1; Nephropontin; Secreted phosphoprotein 1; SPP-1; Urinary stone protein; Uropontin], [SPP1; SPP1; OPN; BNSP; BSPI; ETA-1; BNSP; OPN; SPP-1] |
Gene, Accession # | [OPN], Gene ID: 6696, NCBI: NP_000573.1, UniProt: P10451 |
Catalog # | MBS856687 |
Price | $280 |
Order / More Info | Osteopontin Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Christensen B., Nielsen M.S., Haselmann K.F., Petersen T.E., Sorensen E.S.; Post-translationally modified residues of native human osteopontin are located in clusters: identification of 36 phosphorylation and five O-glycosylation sites and their biological implications.; Biochem. J. 390:285-292(2005). 2. Crosby A.H., Edwards S.J., Murray J.C., Dixon M.J.; Genomic organization of the human osteopontin gene: exclusion of the locus from a causative role in the pathogenesis of dentinogenesis imperfecta type II.; Genomics 27:155-160(1995). |