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Antigenic Specificity | TMEM59 - middle region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Acts as a regulator of autophagy in response to S.aureus infection by promoting activation of LC3 (MAP1LC3A, MAP1LC3B or MAP1LC3C). Acts by interacting with ATG16L1, leading to promote a functional complex between LC3 and ATG16L1 and promoting LC3 lipidation and subsequent activation of autophagy. Modulates the O-glycosylation and complex N-glycosylation steps occurring during the Golgi maturation of several proteins such as APP, BACE1, SEAP or PRNP. Inhibits APP transport to the cell surface and further shedding. |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the middle terminal region of mouse TMEM59 |
Other Names | [transmembrane protein 59; Transmembrane protein 59; transmembrane protein 59; transmembrane protein 59; Thymic dendritic cell-derived factor 1] |
Gene, Accession # | [TMEM59], Gene ID: 56374, NCBI: NP_083841.4, UniProt: Q9QY73 |
Catalog # | MBS3223805 |
Price | $335 |
Order / More Info | TMEM59 - middle region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |