Collagen II, Mouse Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-Collagen II, Mouse antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | Collagen II, Mouse |
| Clone | M2139 |
| Host Species | Mouse |
| Reactive Species | mouse, bovine, chicken, human, rat |
| Isotype | IgG2b |
| Format | unconjugated |
| Size | 0.5 mg |
| Concentration | n/a |
| Applications | Functional Studies (FS), Immuno Assay (IA), Immunohistochemistry (IHC) Paraffin |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The monoclonal antibody M2139 reacts with the J1 epitope (triple helical position 551-564) of collagen type II. Collagen is a structural protein in bone, cartillage and connective tissue. Collagen type II (CII) is the major collagen of the nucleus pulposa (a component of spine), cartilage and vitreous (a component of the eye). The most commonly used animal model for rheumatoid arthritis (RA) is the collagen-induced arthritis (CIA). Transfer of collagen type II specific monoclonal antibodies induces an acute form of arthritis (collagen type II antibody induced arthritis, CAIA). The monocolonal antibody M2139 has been shown to induce CAIA in naive mice after injection of lipopolysacharide (LPS). However, in combination with the monoclonal ant |
| Immunogen | n/a |
| Other Names | n/a |
| Gene, Accession # | n/a |
| Catalog # | MBS584704 |
| Price | $1500 |
| Order / More Info | Collagen II, Mouse Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Nandakumar, K et al; Collagen Type II-specific monoclonal antibody-induced arthritis in mice. Description of the disease and the influence of age, sex and genes. Am J Pathol 2003, 163: 1827 2. Nandakumar, K et al; Collagen type II (CII)-specific antibodies induce arthritis in the absence of T or B cells but the arthritis progression is enhanced by CII-reactive T cells. Arthritis Res Ther 2004, 6: R544 3. Cook, A et al; Urokinase-type plasminogen activator and arthritis progression: role in systemic disease with immune complex involvement. Arthritis Research & Therapy 2010, 12:R37 |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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