Human CD106 Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-Human CD106 antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | Human CD106 |
| Clone | [B-K9] |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | unconjugated |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Flow Cytometry (FC/FACS) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The mouse monoclonal antibody B-K9 recognizes human CD106. CD106 is a 110kDa type 1 transmembrane sialoglycoprotein, which is also known as vascular cell adhesion molecule 1 (VCAM-1). The CD106 protein is primarily expressed on activated vascular endothelium but has also been detected on dendritic cell types, macrophages and non-vascular cells in certain tissues. Expression of CD106 is induced by inflammatory stimuli and cytokines. CD106 binds to the integrins CD49d/CD29 (also known as VLA4) and alpha4beta7 and is important in leucocyte-endothelial cell adhesion and signal transduction. The CD106 protein is thought to play a key role in the migration of leucocyte from the blood into tissues, particularly at sites of inflammation. Studies su |
| Immunogen | Source Note: B-K9 is a mouse monoclonal IgG1 antibody derived by fusion of X63/Ag8.653 mouse myeloma cells with spleen cells from BALB/c mice immunized with activated human umbilical vein endothelial cells. |
| Other Names | [vascular cell adhesion protein 1 isoform a; Vascular cell adhesion protein 1; vascular cell adhesion protein 1; CD106 antigen; vascular cell adhesion molecule 1; INCAM-100; CD_antigen: CD106], [VCAM1; VCAM1; CD106; INCAM-100; L1CAM; V-CAM 1; VCAM-1] |
| Gene, Accession # | [CD106], Gene ID: 7412, NCBI: NP_001069.1, UniProt: P19320 |
| Catalog # | MBS570328 |
| Price | $415 |
| Order / More Info | Human CD106 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1) Wagner BJ, Lob S, Lindau D, Horzer H, Guckel B, Klein G, Glatzle J, Rammensee HG, Brucher BL, Konigsrainer A. Simvastatin reduces tumor cell adhesion to human peritoneal mesothelial cells by decreased expression of VCAM-1 and B1 integrin. Int. J. Oncol. 2011;39(6):1593 - 1600.2) Ticchioni M, Raimondi V, Lamy L, Wijdenes J, Lindberg FP, Brown EJ, Bernard A. Integrin-associated protein (CD47/IAP) contributes to T cell arrest on inflammatory vascular endothelium under flow. FASEB J. 2001; 15:341-350 |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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