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Antigenic Specificity | HDEL |
Clone | [2E7] |
Host Species | Mouse |
Reactive Species | n/a |
Isotype | IgG2b |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | Immunoblot; Immunofluorescence |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: HDEL. This antibody recognizes a ~70 kDa protein corresponding to the predicted molecular mass of HDEL in Drosophila, yeast, and various plants (barnyard grass, beet, cotton, mung bean, sorghum, and wheat). The Hsp70 family includes four highly conserved proteins (Hsp70, Hsc70, Grp75, and Grp78) which function as molecular chaperones, in translocation of polypeptides across cell membranes and to cell nuclei, and in proper folding of nascent polypeptide chains. Sorting of proteins by the Hsp70 family relies on a C-terminal tetrapeptide signal, usually KDEL in animal cells, and HDEL in S. cerevisiae. |
Immunogen | Antigen: Synthetic peptide corresponding to the C-terminus of yeast Bip. Preservative: 0.09% sodium azide |
Other Names | n/a |
Gene, Accession # | [HDEL] |
Catalog # | MBS190517 |
Price | $420 |
Order / More Info | HDEL Antibody from MYBIOSOURCE INC. |
Product Specific References | • Napier RM et al. 1992 J Cell Science 102: 261-271. |