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Antigenic Specificity | WDR77 |
Clone | [8A10-C10-E8] |
Host Species | Mouse |
Reactive Species | human, mouse, rat |
Isotype | IgG1 |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunocytochemistry (ICC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody detects endogenous levels of WDR77 and does not cross-react with related proteins. Non-catalytic component of the 20S PRMT5-containing methyltransferase complex,which modifies specific arginines to dimethylarginines in several spliceosomal Sm proteins and histones.This modification targets Sm proteins to the survival of motor neurons (SMN) complex for assembly into small nuclear ribonucleoprotein core particles.Might play a role in transcription regulation.The 20S PRMT5-containing methyltransferase complex also methylates the Piwi proteins (PIWIL1, PIWIL2 and PIWIL4),methylation of Piwi proteins being required for the interaction with Tudor domain-containing proteins and subsequent localization to the meiotic nuage. |
Immunogen | Immunogen Type: Recombinant Protein Immunogen Description: Purified recombinant human WDR77 protein fragments expressed in E Coli. |
Other Names | [2610312E17Rik; Androgen receptor cofactor p44; C79984; HKMT1069; MEP 50; MEP-50; MEP50; MEP50_HUMAN; Methylosome protein 50; MGC2722; Nbla10071; p44; p44/Mep50; RGD1310479; RP11 552M11.3; WD repeat containing protein 77; WD repeat domain 77] |
Gene, Accession # | [WDR77], Gene ID: 79084, NCBI: NP_077007.1, UniProt: Q9BQA1 |
Catalog # | MBS9400183 |
Price | $200, $255 |
Order / More Info | WDR77 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |