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Antigenic Specificity | Phospho-Rac1/Cdc42 (Ser71) |
Clone | monoclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.03 mg, 0.1 mg, 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Plays a role in the extension and maintenance of the formation of thin, actin-rich surface projections called filopodia. Mediates CDC42-dependent cell migration. |
Immunogen | Immunogen: A synthesized peptide derived from human Phospho-Rac1/Cdc42 (Ser71) Subcellular Localization: Cell membrane; Lipid-anchor; Cytoplasmic side. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Midbody. Localizes to spindle during prometaphase cells. Moves to the central spindle as cells progressed through anaphase to telophase. Localizes at the end of cytokinesis in the intercellular bridge formed between two daughter cells. Its locali |
Other Names | [Cell division control protein 42 homolog; G25K GTP-binding protein; CDC42] |
Gene, Accession # | [Rac1/Cdc42], Gene ID: 998, NCBI: NP_001034891.1, UniProt: P60953 |
Catalog # | MBS1750211 |
Price | $160, $340, $340 |
Order / More Info | Phospho-Rac1/Cdc42 (Ser71) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |