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Antigenic Specificity | mGluR5 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, rat, rabbit |
Isotype | n/a |
Format | epitope affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Flow Cytometry (FC/FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody recognizes ~130 kDa of mGluR 5 Protein. It is cross react to human and rat. The other species are not tested. Glutamate receptors constitute the principal excitatory neurotransmitter receptors in brain. Two classes of glutamate receptors exist: ionotropic receptors, and metabotropic receptors. Ionotropic glutamate receptors are oligomeric complexes of various subunits (GluR1-7, NMDA1-3, KAI-2) which comprise ligand-gated calcium channels. Metabotropic glutamate receptors are G-protein coupled receptors, which when activated can activate phopholipases or adenylylcyclase, depending on the neuron. |
Immunogen | n/a |
Other Names | n/a |
Gene, Accession # | [mGluR5], Gene ID: 2697 |
Catalog # | MBS460151 |
Price | $285 |
Order / More Info | mGluR5 Antibody from MYBIOSOURCE INC. |
Product Specific References | Bonsi P, Cuomo D, De Persis C, Centonze D, Bernardi G, Calabresi P, Pisani A (2005). Modulatory action of metabotropic glutamate receptor (mGluR) 5 on mGluR1 function in striatal cholinergic interneurons. Neuropharmacology 49 Suppl 1: 104 -13. |