SHC1 - C-terminal region Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | SHC1 - C-terminal region |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | cow, dog, guinea pig, horse, human, mouse, rabbit, rat, zebrafish |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This is a rabbit polyclonal antibody against SHC1. It was validated on Western Blot using a cell lysate as a positive control.Target Description: SHC1 is a signaling adapter that couples activated growth factor receptors to signaling pathway. Isoform p46Shc and isoform p52Shc, once phosphorylated, couple activated receptor tyrosine kinases to Ras via the recruitment of the GRB2/SOS complex and are implicated in the cytoplasmic propagation of mitogenic signals. Isoform p46Shc and isoform p52Shc may thus function as initiators of the Ras signaling cascade in various non-neuronal systems. Isoform p66Shc does not mediate Ras activation, but is involved in signal transduction pathways that regulate the cellular response to oxidative stre |
| Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human SHC1 |
| Other Names | [SHC-transforming protein 1 isoform 2; SHC-transforming protein 1; SHC-transforming protein 1; SHC adaptor protein 1; SHC-transforming protein 3; SHC-transforming protein A; Src homology 2 domain-containing-transforming protein C1] |
| Gene, Accession # | [SHC1], Gene ID: 6464, NCBI: NP_003020, UniProt: P29353 |
| Catalog # | MBS3209955 |
| Price | $335 |
| Order / More Info | SHC1 - C-terminal region Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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