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Antigenic Specificity | PREX1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of PREX1 protein. PREX1 (Phosphatidylinositol-3,4,5-Trisphosphate Dependent Rac Exchange Factor 1) is a Protein Coding gene. Diseases associated with PREX1 include Luminal Breast Carcinoma. Among its related pathways are p75 NTR receptor-mediated signalling and RET signaling. The protein encoded by PREX1 acts as a guanine nucleotide exchange factor for the RHO family of small GTP-binding proteins (RACs). It has been shown to bind to and activate RAC1 by exchanging bound GDP for free GTP. The encoded protein, which is found mainly in the cytoplasm, is activated by phosphatidylinositol-3,4,5-trisphosphate and the beta-gamma subunits of heterotrimeric G proteins. |
Immunogen | Immunogen: Synthesized peptide derived from part region of human PREX1 protein at amino acid sequence of 340-420 |
Other Names | [Rabbit PREX1; Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein; P-Rex1; PtdIns(3,4,5)-dependent Rac exchanger 1] |
Gene, Accession # | [PREX1], Gene ID: 57580, NCBI: NP_065871.2, UniProt: Q8TCU6 |
Catalog # | MBS9710542 |
Price | $130, $220, $325 |
Order / More Info | PREX1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |