NFKBIZ Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | NFKBIZ |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: NFKBIZ antibody detects endogenous levels of NFKBIZ. Function: Involved in regulation of NF-kappa-B transcription factor complexes. Inhibits NF-kappa-B activity without affecting its nuclear translocation upon stimulation. Inhibits DNA-binding of RELA and NFKB1/p50, and of the NF-kappa-B p65-p50 heterodimer and the NF-kappa-B p50-p50 homodimer. Seems also to activate NF-kappa-B-mediated transcription. In vitro, upon association with NFKB1/p50 has transcriptional activation activity and, together with NFKB1/p50 and RELA, is recruited to LCN2 promoters. Promotes transcription of LCN2 and DEFB4. Is recruited to IL-6 promoters and activates IL-6 but decreases TNF-alpha production in response to LPS. Seems to be involved in the indu |
| Immunogen | Immunogen: A synthesized peptide derived from human NFKBIZ. Subcellular Location: Nucleus. Aggregated in dot-like structures. Colocalizes with NCOR2. Tissue Specificity: Expressed at high levels in peripheral blood leukocytes and lung, at moderate levels in liver, placenta, and at low levels in spleen, kidney, skeletal muscle and heart. Predicted Cross Reactivity: Bovine, Horse, Sheep, Rabbit Similarity: Bovine (83%), Horse (83%), Sheep (83%), Rabbit (92%) |
| Other Names | [FLJ30225; FLJ34463; I-kappa-B-zeta; Ikappa B zeta; IkappaB zeta; IkappaBzeta; IkB-zeta; IKBZ; IKBZ_HUMAN; IKBzeta; IL-1 inducible nuclear ankyrin-repeat protein; INAP; MAIL; MAIL protein; Molecule possessing ankyrin repeats induced by lipopolysaccharide; NF-kappa-B inhibitor zeta; NFKBIZ; Nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor zeta] |
| Gene, Accession # | [NFKBIZ], Gene ID: 64332, NCBI: NP_001005474.1, UniProt: Q9BYH8 |
| Catalog # | MBS9603657 |
| Price | $240, $280 |
| Order / More Info | NFKBIZ Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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