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Antigenic Specificity | SENP6 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Immunohistochemistry (IHC) Paraffin, ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: SENP6 Polyclonal Antibody detects endogenous levels of SENP6 protein. Ubiquitin-like molecules (UBLs), such as SUMO1 (UBL1; MIM 601912), are structurally related to ubiquitin (MIM 191339) and can be ligated to target proteins in a similar manner as ubiquitin. However, covalent attachment of UBLs does not result in degradation of the modified proteins. SUMO1 modification is implicated in the targeting of RANGAP1 (MIM 602362) to the nuclear pore complex, as well as in stabilization of I-kappa-B-alpha (NFKBIA; MIM 164008) from degradation by the 26S proteasome. Like ubiquitin, UBLs are synthesized as precursor proteins, with 1 or more amino acids following the C-terminal glycine-glycine residues of the mature UBL protein. Thus, th |
Immunogen | Immunogen: Synthesized peptide derived from the C-terminal region of human SENP6 at AA rangle: 1010-1090 |
Other Names | [Rabbit SENP6; SENP6; KIAA0797; SSP1; SUSP1; FKSG6; Sentrin-specific protease 6; SUMO-1-specific protease 1; Sentrin/SUMO-specific protease SENP6] |
Gene, Accession # | [SENP6], Gene ID: 26054, NCBI: NP_001093879.1, UniProt: Q9GZR1 |
Catalog # | MBS9705104 |
Price | $130, $220, $325 |
Order / More Info | SENP6 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |