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Antigenic Specificity | IL-36A |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: IL-36A antibody is human specific. IL-36A antibody will not cross-react with IL-36B or IL-36G. IL-36A is is a member of the interleukin 1 cytokine family whose gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2 (1). IL-36A is thought to activate the NF-kappaB pathway through IL-1 receptor family members IL-1RL2 and IL-1RAcP (2). Like the related proteins IL-36B and IL-36G, IL-36A requires post-translational processing for full agonist activity, but the cleavage mechanism is currently unknown (3). The IL-36 cytokines have been suggested to amplify Th1 responses by enhancing proliferation and Th1 polarization of naive CD4+ T cells (4). |
Immunogen | Immunogen: IL-36A antibody was raised against an 11 amino acid peptide near the carboxy terminus of human IL-36A. Buffer: IL-36A antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [IL-36A; FIL1; FIL1E; IL1F6; IL-1F6; IL1(EPSILON); FIL1(EPSILON); IL1E; Interleukin-36 alpha; FIL1 epsilon; IL-1 epsilon; interleukin 36, alpha], [IL36A; IL36A; FIL1; FIL1E; IL1F6; IL-1F6; IL1(EPSILON); FIL1(EPSILON); FIL1E; IL1E; IL1F6; IL-1 epsilon; IL-1F6] |
Gene, Accession # | [IL36A], Gene ID: 27179, NCBI: NP_055255, UniProt: Q9UHA7 |
Catalog # | MBS153528 |
Price | $375 |
Order / More Info | IL-36A Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |