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Antigenic Specificity | Mouse EGFR |
Clone | monoclonal |
Host Species | Rabbit |
Reactive Species | mouse |
Isotype | IgG |
Format | unconjugated |
Size | 0.06 mL, 0.12 mL, 0.2 mL |
Concentration | n/a |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-alpha, betacellulin, etc. EGFR protein plays a crucial role in signaling pathway in the regulation of cell proliferation, survival and differentiation. Binding of a ligand induces EGFR protein homo- or heterodimerization, the subsequent tyrosine autophosphorylation and initiates various down stream pathways (MAPK, PI3K/PKB and STAT). In addition, EGFR signaling also has been shown to exert action on carcinogenesis and disease progression, and thus EGFR protein is proposed as a target for cancer therapy currently. |
Immunogen | Immunogen: Recombinant Mouse EGFR/ErbB1/HER1 protein Buffer: 0.2 mum filtered solution in PBS with 5% trehalose |
Other Names | [epidermal growth factor receptor, partial] |
Gene, Accession # | [EGFR ] |
Catalog # | MBS2544682 |
Price | $215, $330, $500 |
Order / More Info | Mouse EGFR Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |