Semaphorin-3A (Central Region) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificitySemaphorin-3A (Central Region)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, rat, mouse
Isotypen/a
Formataffinity purified
Size0.1 mL
Concentrationn/a
ApplicationsELISA, Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC)
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DescriptionThe antibody detects a 95kDa* protein corresponding to the apparent molecular mass of Sema3A on SDS-PAGE immunoblots of human recombinant Sema3A and neonatal rat brain lysates. One family of inhibitory axon guidance molecules is the semaphorins. The semaphorins include secreted, transmembrane, and GPI-anchoredextracellular molecules that are involved in regulating axon guidance by inhibiting axons from growing toward incorrect targets. Semaphorin 3A(Sema3A) may play a particularly interesting role in limiting axon regeneration since it is expressed in meningeal fibroblasts that invade the injured spinal cord and surround the glial scar. In addition, the Sema3A co-receptors, Neuropilin-1 and Plexin-A1, are expressed on axons that regenerat
ImmunogenImmunogen: Semaphorin 3A synthetic peptide (coupled to carrier protein) corresponding to amino acids in the central region of human Sema3A. The sequence used is highly conserved in rat and mouse Sema3A, and has low homology to other semaphorin family members.
Other Names[Sema3A; Semaphorin III], [SEMA3A; SEMA3A; SemD; SEMA1; SEMAD; SEMAL; coll-1; Hsema-I; SEMAIII; Hsema-III; MGC133243; SEMAD]
Gene, Accession #Gene ID: 10371, NCBI: NP_006071.1, UniProt: Q14563
Catalog #MBS472057
Price$385
Order / More InfoSemaphorin-3A (Central Region) Antibody from MYBIOSOURCE INC.
Product Specific References• Kolodokin, A.L. et al. (1993) Cell 75:1389.• Luo, Y. et al. (1993) Cell 75:217.• Pasterkamp, R.J. & Verhaagen, J. (2001) Brain Res Rev 35:36.• Tang, X-Q. et al. (2007) J. Neurosci. 27(22):6068 (WB: R. E14 spinal cord)
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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