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Antigenic Specificity | Semaphorin-3A (Central Region) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, rat, mouse |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | ELISA, Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects a 95kDa* protein corresponding to the apparent molecular mass of Sema3A on SDS-PAGE immunoblots of human recombinant Sema3A and neonatal rat brain lysates. One family of inhibitory axon guidance molecules is the semaphorins. The semaphorins include secreted, transmembrane, and GPI-anchoredextracellular molecules that are involved in regulating axon guidance by inhibiting axons from growing toward incorrect targets. Semaphorin 3A(Sema3A) may play a particularly interesting role in limiting axon regeneration since it is expressed in meningeal fibroblasts that invade the injured spinal cord and surround the glial scar. In addition, the Sema3A co-receptors, Neuropilin-1 and Plexin-A1, are expressed on axons that regenerat |
Immunogen | Immunogen: Semaphorin 3A synthetic peptide (coupled to carrier protein) corresponding to amino acids in the central region of human Sema3A. The sequence used is highly conserved in rat and mouse Sema3A, and has low homology to other semaphorin family members. |
Other Names | [Sema3A; Semaphorin III], [SEMA3A; SEMA3A; SemD; SEMA1; SEMAD; SEMAL; coll-1; Hsema-I; SEMAIII; Hsema-III; MGC133243; SEMAD] |
Gene, Accession # | Gene ID: 10371, NCBI: NP_006071.1, UniProt: Q14563 |
Catalog # | MBS472057 |
Price | $385 |
Order / More Info | Semaphorin-3A (Central Region) Antibody from MYBIOSOURCE INC. |
Product Specific References | • Kolodokin, A.L. et al. (1993) Cell 75:1389.• Luo, Y. et al. (1993) Cell 75:217.• Pasterkamp, R.J. & Verhaagen, J. (2001) Brain Res Rev 35:36.• Tang, X-Q. et al. (2007) J. Neurosci. 27(22):6068 (WB: R. E14 spinal cord) |