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Antigenic Specificity | JNK1/2/3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat, cow, dog, monkey, zebrafish |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunoprecipitation (IP) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Entrez Summary: Serine/threonine-protein kinase involved in various processes such as cell proliferation, differentiation, migration, transformation and programmed cell death. Extracellular stimuli such as proinflammatory cytokines or physical stress stimulate the stress-activated protein kinase/c-Jun N-terminal kinase (SAP/JNK) signaling pathway. In this cascade, two dual specificity kinases MAP2K4/MKK4 and MAP2K7/MKK7 phosphorylate and activate MAPK8/JNK1. In turn, MAPK8/JNK1 phosphorylates a number of transcription factors, primarily components of AP-1 such as JUN, JDP2 and ATF2 and thus regulates AP-1 transcriptional activity. |
Immunogen | Immunogen: A synthesized peptide derived from human JNK1+JNK2+JNK3. Sensitivity: JNK1+JNK2+JNK3 Antibody detects endogenous levels of total JNK1+JNK2+JNK3 |
Other Names | [c-Jun N-terminal kinase 3; FLJ12099; FLJ33785; JNK1; JNK2; JNK3; JNK3 alpha protein kinase; JNK3A; MAP kinase 10; MAP kinase p49 3F12; MAPK 10; MAPK10], [MAPK8; MAPK8; JNK; JNK1; PRKM8; SAPK1; JNK-46; JNK1A2; SAPK1c; JNK21B1/2; JNK1; PRKM8; SAPK1; SAPK1C; MAP kinase 8; MAPK 8; SAPK1c] |
Gene, Accession # | [JNK1/2/3], Gene ID: 5599, NCBI: NP_001265476.1, UniProt: P45983 |
Catalog # | MBS477183 |
Price | $335 |
Order / More Info | JNK1/2/3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |