Edit |   |
---|---|
Antigenic Specificity | SDCBP2 (N-term), 98-127 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This SDCBP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 98-127 amino acids from the N-terminal region of human SDCBP2. Syntenin 2 binds to the cytoplasmic domains of the syndecans: it contains a tandem repeat of PDZ domains that reacts with the FYA (phe-tyr-ala) C-terminal amino acid sequence of the syndecans. Cells that overexpress the fusion protein show numerous cell surface extensions, suggesting that Syntenin 2 may have an effect on cytoskeleton-membrane organization. Therefore, Syntenin 2 may function as an adaptor that couples syndecans to cytoskeletal proteins or cytosolic downstream signal-effectors. |
Immunogen | n/a |
Other Names | [Syntenin-2; Syndecan-binding protein 2; SDCBP2; SITAC18] |
Gene, Accession # | [SDCBP2], Gene ID: 27111, NCBI: NP_001186713.1, UniProt: Q9H190 |
Catalog # | MBS9214845 |
Price | $165, $370 |
Order / More Info | SDCBP2 (N-term), 98-127 Antibody from MYBIOSOURCE INC. |
Product Specific References | Wang, A.G., et al. Biochem. Biophys. Res. Commun. 345(3):1022-1032(2006) Deloukas, P., et al. Nature 414(6866):865-871(2001) Koroll, M., et al. J. Biol. Chem. 276(14):10646-10654(2001) Borrell-Pages, M., et al. Mol. Biol. Cell 11(12):4217-4225(2000) |