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Antigenic Specificity | MRGX2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of MRGX2 protein. Mast cell-specific receptor for basic secretagogues, i.e. Cationic amphiphilic drugs, as well as endo- or exogenous peptides, consisting of a basic head group and a hydrophobic core (PubMed: 25517090). Recognizes and binds small molecules containing a cyclized tetrahydroisoquinoline (THIQ), such as non-steroidal neuromuscular blocking drugs (NMBDs), including tubocurarine and atracurium. In response to these compounds, mediates pseudo-allergic reactions characterized by histamine release, inflammation and airway contraction (By similarity). Acts as a receptor for a number of other ligands, including peptides and alkaloids, such as cortistatin-14, proadrenomedullin N-terminal peptides |
Immunogen | Immunogen: Synthesized peptide derived from part region of human MRGX2 protein at amino acid sequence of 250-330 |
Other Names | [Rabbit MRGX2; Mas-related G-protein coupled receptor member X2] |
Gene, Accession # | [MRGX2], Gene ID: 117194, NCBI: NP_473371.1, UniProt: Q96LB1 |
Catalog # | MBS9709878 |
Price | $130, $220, $325 |
Order / More Info | MRGX2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |