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Antigenic Specificity | ErbB-4 (Phospho Tyr1284) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, Immunofluorescence (IF), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-ErbB-4 (Y1284) Polyclonal Antibody detects endogenous levels of ErbB-4 protein only when phosphorylated at Y1284. ERBB4 is a member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily. It encodes a single-pass type I membrane protein with multiple cysteine rich domains, a transmembrane domain, a tyrosine kinase domain, a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif. The erb-b2 receptor tyrosine kinase 4 binds to and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation. Multiple proteolytic events allow for the release of a cytoplasmic fragment and an extracellular fragment. Mutation |
Immunogen | Immunogen: Synthesized peptide derived from human ErbB-4 around the phosphorylation site of Y1284 |
Other Names | [Rabbit ErbB-4 (phospho Tyr1284); ERBB4; HER4; Receptor tyrosine-protein kinase erbB-4; Proto-oncogene-like protein c-ErbB-4; Tyrosine kinase-type cell surface receptor HER4; p180erbB4] |
Gene, Accession # | [ERBB-4], Gene ID: 2066, NCBI: NP_001036064.1, UniProt: Q15303 |
Catalog # | MBS9704799 |
Price | $130, $220, $325 |
Order / More Info | ErbB-4 (Phospho Tyr1284) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |