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Antigenic Specificity | GAD65 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Rabbit IgG polyclonal antibody for Glutamate decarboxylase 2(GAD2) detection. Tested with WB, IHC-P in Human, Mouse, Rat. Background: Glutamate decarboxylase or glutamic acid decarboxylase(GAD) is an enzyme that catalyzes the decarboxylation of glutamate to GABA and CO2. GAD65 is the isoform with molecular weight of 65 kDa. Karlsen et al.(1991) mapped the GAD2 gene to chromosome 10p13-p11.2 by in situ hybridization. Bu et al.(1992) isolated a cDNA corresponding to the GAD2 gene from a human brain cDNA library. The deduced 585-amino acid protein has a molecular mass of 65 kD. GAD65 is target of autoantibodies in people who later develop type 1 diabetes mellitus or latent autoimmune diabetes. |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human GAD65 (21-37aa ENPGTARAWCQVAQKFT), identical to the related mouse and rat sequences. |
Other Names | [Glutamate decarboxylase 2; glutamate decarboxylase 2(pancreatic islets and brain, 65kDa); 65 kDa glutamic acid decarboxylase; DCE 2; DCE2; DCE2_HUMAN; GAD 2; GAD 65; GAD-2; GAD-65; Gad2; Glutamate decarboxylase 2(pancreas); Glutamate Decarboxylase 2(pancreatic islets and brain 65kDa); Glutamate decarboxylase 2; Glutamate Decarboxylase 65; Glutamate decarboxylase 65 kDa isoform; Glutamic Acid Decarboxylase 2; Glutamic Acid Decarboxylase 65; MGC161605; MGC161607], [GAD2; GAD2; GAD65; GAD65; GAD-65] |
Gene, Accession # | [GAD2], Gene ID: 2572, NCBI: Q05329.1, UniProt: Q05329 |
Catalog # | MBS175471 |
Price | $315 |
Order / More Info | GAD65 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |