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Antigenic Specificity | CD40/Tnfrsf5 Picoband |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse, rat |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This CD40 gene is a member of the TNF-receptor superfamily. The encoded protein is a receptor on antigen-presenting cells of the immune system and is essential for mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. AT-hook transcription factor AKNA is reported to coordinately regulate the expression of this receptor and its ligand, which may be important for homotypic cell interactions. Adaptor protein TNFR2 interacts with this receptor and serves as a mediator of the signal transduction. The interaction of this receptor and its ligand is found to be necessary for amyloid-beta-induced microglial activation, and th |
Immunogen | Immunogen: E Coli-derived rat CD40 recombinant protein (Position: V24-R193). |
Other Names | [CD40 molecule; CD40 molecule; TNF receptor superfamily member 5; Tumor necrosis factor receptor superfamily, member 5, isoform CRA_a; Cd40; Tnfrsf5; rCG_32260] |
Gene, Accession # | [CD40/Tnfrsf5], Gene ID: 171369, NCBI: NP_599187.1, UniProt: Q4QQW2 |
Catalog # | MBS1750321 |
Price | $280 |
Order / More Info | CD40/Tnfrsf5 Picoband Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |