FZD10 (N-term) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityFZD10 (N-term)
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciesmouse
Isotypen/a
Formatpurified
Size0.08 mL, 0.4 mL
Concentrationvial concentration: 0.5
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionThis FZD10 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 177-212 amino acids from the N-terminal region of human FZD10. Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK- 3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to in
Immunogenn/a
Other Names[Frizzled-10; Fz-10; hFz10; FzE7; CD350; FZD10]
Gene, Accession #[FZD10], Gene ID: 11211, NCBI: NP_009128.1, UniProt: Q9ULW2
Catalog #MBS9201169
Price$165, $370
Order / More InfoFZD10 (N-term) Antibody from MYBIOSOURCE INC.
Product Specific ReferencesKoike J.,et al.Biochem. Biophys. Res. Commun. 262:39-43(1999). Tanaka S.,et al.Proc. Natl. Acad. Sci. U.S.A. 95:10164-10169(1998). Kwon H.S.,et al.Mol. Cell. Biol. 29:2139-2154(2009).
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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