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Antigenic Specificity | CARD8 (Caspase Recruitment Domain, Cardinal/TUCAN) |
Clone | [8C55] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | Protein G purified |
Size | 0.05 mg |
Concentration | 0.1 mg/ml |
Applications | Western Blot (WB), Immunoprecipitation (IP), Immunocytochemistry (ICC), Flow Cytometry (FC/FACS), Immunofluorescence (IF), Dot Blot (DB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes human CARD8. Apoptosis is related to many diseases and development. Cell death signals are transduced by death domain (DD), death effector domain (DED), and caspase recruitment domain (CARD) containing molecules. CARD containing proteins include some caspases, Apaf-1, CARD4, IAPs, RICK, ARC, RAIDD, BCL-10, and ASC. A novel CARDcontaining protein was recently identified and designated CARD8. This protein interacts with DRAL, a p53-responsive protein implicated in the induction of apoptosis, and caspase-1 and its related proteins ICEBERG and pesudo- ICE. Although there are conflicting reports on whether CARD8 acts a pro- or anti-apoptotic protein, it has been suggested that it functions as an adaptor molecule regulating caspase-1 a |
Immunogen | Immunogen: Partial recombinant sequence from human CARD8 |
Other Names | [-CARD8 (Caspase Recruitment Domain, Cardinal/TUCAN)], [CARD8; CARD8; NDPP; DACAR; DAKAR; NDPP1; TUCAN; CARDINAL; FLJ18119; FLJ18121; KIAA0955; MGC57162; DKFZp779L0366; KIAA0955; NDPP1] |
Gene, Accession # | Gene ID: 22900, NCBI: NP_055774.1, UniProt: Q9Y2G2 |
Catalog # | MBS600245 |
Price | $435 |
Order / More Info | CARD8 (Caspase Recruitment Domain, Cardinal/TUCAN) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |