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Antigenic Specificity | BSG |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous level of total BSG protein. Basigin (EMMPRIN, CD147) is a type I integral membrane receptor protein belonging to the immunoglobulin superfamily (1). Basigin is a glycosylated protein with four known isoforms, of which isoform 2 is the most abundantly expressed (2). Multiple functions have been ascribed to Basigin; foremost among these is stimulating the secretion of extracellular matrix metalloproteinases by adjacent fibroblasts, a function which has been implicated in promoting tumor progression (2-4). Research studies have shown that Basigin is overexpressed by many tumor cells, and its expression level may correlate with tumor malignancy (5,6). A recent study identified the BASIGIN gene as a regulatory tar |
Immunogen | Immunogen Type: Recombinant Protein Immunogen Description: Recombinant protein of human BSG. |
Other Names | [5F7; CD147; EMMPRIN; M6; OK] |
Gene, Accession # | [BSG], Gene ID: 682, NCBI: NP_001719.2, UniProt: P35613 |
Catalog # | MBS9409061 |
Price | $255 |
Order / More Info | BSG Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |