RIG-I Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | RIG-I |
| Clone | [ABM40B5] |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1, kappa |
| Format | Protein G purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Immunohistochemistry (IHC),Flow Cytometry (FACS), Western blot (WB). |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | RIG-I or Probable ATP-dependent RNA helicase DDX58 or simply DDX58 is a RNA helicase enzyme with two isoforms (106 and 101 kDa). RIG-I belongs to the DEAD/H box family and is involved in several cellular responses including RNA binding and alteration of RNA secondary structure. RIG-1 acts as sensor of viral nucleic acids thus activating a cascade of antiviral responses including the induction of type I interferons and pro-inflammatory cytokines. Generally it remains as a monomer but upon activation by viral dsRNA it homomultimerizes and interacts with mitochondria antiviral signaling protein (MAVS/IPS1) which activating a cascade of reactions to produce specific interferon. RIG-1 is mostly expressed in vascular smooth cells. |
| Immunogen | Immunogen: A partial length recombinant human RIG-I protein (amino acids 1-220) was used as the immunogen for this antibody. |
| Other Names | [probable ATP-dependent RNA helicase DDX58; Probable ATP-dependent RNA helicase DDX58; probable ATP-dependent RNA helicase DDX58; DEAD box protein 58; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide; RNA helicase RIG-I; retinoic acid-inducible gene 1 protein; retinoic acid-inducible gene I protein; DEAD (Asp-Glu-Ala-Asp) box polypeptide 58; DEAD box protein 58; RIG-I-like receptor 1; RLR-1; Retinoic acid-inducible gene 1 protein; RIG-1; Retinoic acid-inducible gene I protein; RIG-I], [DDX58; DDX58; RIGI; RIG-I; RLR-1; SGMRT2; RLR-1; RIG-1; RIG-I] |
| Gene, Accession # | [RIG-I], Gene ID: 23586, NCBI: NP_055129.2, UniProt: O95786 |
| Catalog # | MBS668020 |
| Price | $270 |
| Order / More Info | RIG-I Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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