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Antigenic Specificity | HO-1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat, dog, rabbit, sheep |
Isotype | n/a |
Format | Protein A purified |
Size | 0.05 mg, 1 mg |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Paraffin, Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes human, mouse, rat, dog, rabbit, and sheep HO-1. Detects a band of ~32kDa by Western blot. Heme Oxygenase-1 (HO-1) also known as Hsp32, is the inducible isoform of heme oxygenase that catalyzes the NADPH, oxygen, and cytochrome P450 reductase dependent oxidation of heme to carbon monoxide, ferrous iron and biliverdin which is rapidly reduced to bilirubin. These products of the HO reaction have important physiological effects: carbon monoxide is a potent vasodilator and has been implicated to be a physiological regulator of cGMP and vascular tone; biliverdin and its product bilirubin are potent antioxidants; free iron increases oxidative stress and regulates the expression of many mRNAs (e.g., DCT-1, ferritin and transferring rec |
Immunogen | Immunogen: Recombinant rat HO-1 (Hsp32) lacking the membrane spanning region. |
Other Names | [HMOX1; Hsp32; Heat shock protein 32; Heme oxygenase 1], [Hmox1; Hmox1; Ho1; Heox; Hmox; Ho-1; HEOXG; hsp32; HO-1] |
Gene, Accession # | [HO-1], Gene ID: 24451, NCBI: P06762.1, UniProt: P06762 |
Catalog # | MBS565261 |
Price | $250, $1740 |
Order / More Info | HO-1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |