CD40, Mouse Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | CD40, Mouse |
| Clone | [FGK45.5] |
| Host Species | Rat |
| Reactive Species | mousedoes not react with human. |
| Isotype | IgG2a, kappa |
| Format | purified |
| Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
| Concentration | n/a |
| Applications | Functional Studies, Flow Cytometry (FC/FACS), Immunofluorescence (IF) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Upon binding to its ligand CD154, CD40 acts as a costimulatory molecule for the activation of B cells, dendritic cells, monocytes, and other APCs. CD40 plays roles in B cell activation, differentiation, proliferation and Ig isotype switching as well as dendritic cell maturation. FGK4.5 can be used for blocking of CD40/CD154 interaction and forin vitroandin vivoactivation of CD40 expressing APCs. This MAb is shown to indirectly activate natural killer (NK) cells, producing significant antitumor and anti-metastatic effects. Effective in boosting immune responses against infectious agents and can potentially be used to treat chronic autoimmune inflammatory processes. |
| Immunogen | Immunogen: Purified recombinant Mouse CD40 fusion protein |
| Other Names | [B cell surface antigen CD40; CD40 type II isoform; p50; Bp50; CD40L receptor; CDW40; TRAP; IMD3; IGM; Tnfrsf5; HIGM1; GP39; T-BAM] |
| Gene, Accession # | [CD40], Gene ID: 21939, NCBI: P27512.3, UniProt: P27512 |
| Catalog # | MBS4381532 |
| Price | $190, $340, $340 |
| Order / More Info | CD40, Mouse Antibody from MYBIOSOURCE INC. |
| Product Specific References | Agonistic Anti-CD40 Antibody Profoundly Suppresses the Immune Response to Infection with Lymphocytic Choriomeningitis Virus C. Bartholdy, et al. J. Immunol. 178 1662 (2007) |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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