STUB1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificitySTUB1
Clonemonoclonal
Host SpeciesMouse
Reactive Specieshuman, mouse, rat
IsotypeIgG2b
Formatimmunogen affinity purified
Size0.1 mg
Concentrationn/a
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC) Paraffin
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DescriptionSpecificity: No cross reactivity with other proteins. Description: Mouse IgG monoclonal antibody for STUB1 detection. Tested with WB, IHC-P in Human; Mouse; Rat.Background: STUB1 (STIP1 homology and U-Box containing protein 1), also known as CHIP (C terminus of HSC70-Interacting Protein), is a human gene. This gene encodes a protein containing tetratricopeptide repeat and a U-box that functions as a ubiquitin ligase/cochaperone. The encoded protein binds to and ubiquitinates shock cognate 71 kDa protein (Hspa8) and DNA polymerase beta (Polb), among other targets. Mutations in this gene cause spinocerebellar ataxia, autosomal recessive 16. Alternative splicing results in multiple transcript variants. There is a pseudogene for this gene o
ImmunogenImmunogen: E.coli-derived human STUB1 recombinant protein (Position: R51-Y303).
Other Names[E3 ubiquitin-protein ligase CHIP; STIP1 homology and U-box containing protein 1; Antigen NY-CO-7; CLL-associated antigen KW-8; Carboxy terminus of Hsp70-interacting protein; RING-type E3 ubiquitin transferase CHIP; STIP1 homology and U box-containing protein 1; STUB1; CHIP; PP1131]
Gene, Accession #[STUB1], Gene ID: 10273, NCBI: NP_001280126.1, UniProt: Q9UNE7
Catalog #MBS1752073
Price$315
Order / More InfoSTUB1 Antibody from MYBIOSOURCE INC.
Product Specific References1. Entrez Gene: STUB1 STIP1 homology and U-box containing protein 1. 2. Heimdal, K., Sanchez-Guixe, M., Aukrust, I., Bollerslev, J., Bruland, O., Jablonski, G. E., Erichsen, A. K., Gude, E., Koht, J. A., Erdal, S., Fiskerstrand, T., Haukanes, B. I., Boman, H., Bjorkhaug, L., Tallaksen, C. M. E., Knappskog, P. M., Johansson, S. STUB1 mutations in autosomal recessive ataxias--evidence for mutation-specific clinical heterogeneity. Orphanet J. Rare Dis. 9: 146, 2014.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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