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Antigenic Specificity | Human AP-2 complex subunit sigma |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peroxidase (HRP) conjugate |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein Transport via Transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but is itself unable to bind directly to membrane components. Clathrin-associated adaptor protein (AP) complexes which can bind directly to both the clathrin lattice and to the lipid and |
Immunogen | Immunogen: Recombinant human AP-2 complex subunit sigma protein |
Other Names | [AP-2 complex subunit sigma isoform 3; AP-2 complex subunit sigma; AP-2 complex subunit sigma; adaptor related protein complex 2 sigma 1 subunit; Adaptor protein complex AP-2 subunit sigma; Adaptor-related protein complex 2 subunit sigma; Clathrin assembly protein 2 sigma small chain; Clathrin coat assembly protein AP17; Clathrin coat-associated protein AP17; HA2 17 kDa subunit; Plasma membrane adaptor AP-2 17 kDa protein; Sigma2-adaptin], [AP2S1; AP2S1; AP17; FBH3; HHC3; FBHOk; CLAPS2; AP17; CLAPS2] |
Gene, Accession # | Gene ID: 1175, NCBI: NP_001288005.1, UniProt: P53680 |
Catalog # | MBS715769 |
Price | $160, $235 |
Order / More Info | Human AP-2 complex subunit sigma Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |