LRTOMT Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityLRTOMT
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatimmunogen affinity purified
Size0.1 mg
Concentrationn/a
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC) Paraffin
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DescriptionSpecificity: No cross reactivity with other proteins. Description: Rabbit IgG polyclonal antibody for LRTOMT detection. Tested with WB, IHC-P in Human; Mouse; Rat.Background: Leucine rich transmembrane and O-methyltransferase domain containing is a protein that in humans is encoded by the LRTOMT gene. It is mapped to 11q13.4. This gene has evolved in primates as a fusion of two ancestral neighboring genes, Lrrc51 and Tomt, which exist as two independent genes in rodents. The fusion gene contains some shared exons, but encodes structurally unrelated proteins, LRTOMT1 and LRTOMT2. Those variants that utilize the more centromere-proximal 3' terminal exon (short transcript form) encode LRTOMT1, while those variants that use a more centr
ImmunogenImmunogen: A synthetic peptide corresponding to a sequence of human LRTOMT (RLLTVERDPRTAAVAEKLIRLAGFDEHMVEL).
Other Names[Transmembrane O-methyltransferase; Catechol O-methyltransferase 2; Protein LRTOMT2; LRTOMT; COMT2]
Gene, Accession #[LRTOMT], Gene ID: 220074, NCBI: NP_001138780.1, UniProt: Q8WZ04
Catalog #MBS1752876
Price$315
Order / More InfoLRTOMT Antibody from MYBIOSOURCE INC.
Product Specific References1. Charif M, Bounaceur S, Abidi O, Nahili H, Rouba H, Kandil M, Boulouiz R, Barakat A (December 2012). The c.242G>A mutation in LRTOMT gene is responsible for a high prevalence of deafness in the Moroccan population. Molecular Biology Reports. 39 (12): 11011-6. 2. Entrez Gene: Leucine rich transmembrane and O-methyltransferase domain containing 3. Riahi Z, Bonnet C, Zainine R, Louha M, Bouyacoub Y, Laroussi N, Chargui M, Kefi R, Jonard L, Dorboz I, Hardelin JP, Salah SB, Levilliers J, Weil D, McElreavey K, Boespflug OT, Besbes G, Abdelhak S, Petit C (2014). Whole exome sequencing identifies new causative mutations in Tunisian families with non-syndromic deafness. PLoS One. 9 (6): e99797.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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