NSUN2 (Center), 423-451 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | NSUN2 (Center), 423-451 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.5 |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This NSUN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 423-451 amino acids from the Central region of human NSUN2. Maturation of cytoplasmic tRNAs includes splicing ofintrons, which are located 1 nucleotide 3-prime from the anticodonin all intron-containing tRNA genes. In tRNA-leu(CAA), the firstposition of the anticodon, C34, is converted to 5-methylcytosine, amodification necessary to stabilize the anticodon-codon pairing andcorrectly translate the mRNA. NSUN2 encodes a methyltransferasethat catalyzes the intron-dependent formation of 5-methylcytosineat C34 of tRNA-leu(CAA) (Brzezicha et al., 2006 [PubMed17071714]). |
| Immunogen | n/a |
| Other Names | [tRNA (cytosine(34)-C(5))-methyltransferase; Myc-induced SUN domain-containing protein; Misu; NOL1/NOP2/Sun domain family member 2; Substrate of AIM1/Aurora kinase B; tRNA (cytosine-5-)-methyltransferase; tRNA methyltransferase 4 homolog; hTrm4; NSUN2; SAKI; TRM4] |
| Gene, Accession # | [NSUN2], Gene ID: 54888, NCBI: NP_001180384.1, UniProt: Q08J23 |
| Catalog # | MBS9213116 |
| Price | $165, $370 |
| Order / More Info | NSUN2 (Center), 423-451 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Bailey, S.D., et al. Diabetes Care (2010) In press : Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) : Frye, M., et al. Cancer Lett. 289(1):71-80(2010) Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009) Hussain, S., et al. J. Cell Biol. 186(1):27-40(2009) |
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MYBIOSOURCE INC.
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