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Antigenic Specificity | NSMCE2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | fluorescein (FITC) conjugate |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | E3 SUMO-protein ligase component of the SMC5-SMC6 complex, a complex involved in DNA double-strand break repair by homologous recombination. Is not be required for the stability of the complex. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination in ALT (alternative lengthening of telomeres) cell lines and mediates sumoylation of shelterin complex (telosome) components which is proposed to lead to shelterin complex disassembly in ALT-associated PML bodies (APBs). Acts as a E3 ligase mediating SUMO attachment to various proteins such as SMC6L1 and TRAX, the shelterin complex subunits TERF1, TERF |
Immunogen | Immunogen: Recombinant human E3 SUMO-protein ligase NSE2 protein Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-87338 / sc-87339 |
Other Names | [E3 SUMO-protein ligase NSE2 (EC:6.3.2.-); NSMCE2; C8orf36; MMS21; MMS21 homolog; hMMS21; Non-structural maintenance of chromosomes element 2 homolog; Non-SMC element 2 homolog], [NSMCE2; NSMCE2; NSE2; MMS21; ZMIZ7; C8orf36; C8orf36; MMS21; hMMS21; Non-SMC element 2 homolog] |
Gene, Accession # | [NSMCE2], Gene ID: 286053, NCBI: NP_775956.1, UniProt: Q96MF7 |
Catalog # | MBS1492971 |
Price | $160, $235 |
Order / More Info | NSMCE2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |