NSMCE2 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityNSMCE2
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatfluorescein (FITC) conjugate
Size0.05 mg, 0.1 mg
Concentrationn/a
ApplicationsELISA (EIA)
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DescriptionE3 SUMO-protein ligase component of the SMC5-SMC6 complex, a complex involved in DNA double-strand break repair by homologous recombination. Is not be required for the stability of the complex. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination in ALT (alternative lengthening of telomeres) cell lines and mediates sumoylation of shelterin complex (telosome) components which is proposed to lead to shelterin complex disassembly in ALT-associated PML bodies (APBs). Acts as a E3 ligase mediating SUMO attachment to various proteins such as SMC6L1 and TRAX, the shelterin complex subunits TERF1, TERF
ImmunogenImmunogen: Recombinant human E3 SUMO-protein ligase NSE2 protein Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-87338 / sc-87339
Other Names[E3 SUMO-protein ligase NSE2 (EC:6.3.2.-); NSMCE2; C8orf36; MMS21; MMS21 homolog; hMMS21; Non-structural maintenance of chromosomes element 2 homolog; Non-SMC element 2 homolog], [NSMCE2; NSMCE2; NSE2; MMS21; ZMIZ7; C8orf36; C8orf36; MMS21; hMMS21; Non-SMC element 2 homolog]
Gene, Accession #[NSMCE2], Gene ID: 286053, NCBI: NP_775956.1, UniProt: Q96MF7
Catalog #MBS1492971
Price$160, $235
Order / More InfoNSMCE2 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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