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Antigenic Specificity | MLIP |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: At least three isoforms of MLIP are known to exist. MLIP Antibody: The muscle-enriched A-type lamin-interacting protein (MLIP) is ubiquitously expressed, although most predominantly in heart, skeletal and smooth muscle, and interacts directly and co-localizes with lamin A and C in the nuclear envelope. MLIP also co-localizes with promyelocytic leukemia (PML) bodies within the nucleus. Decreasing lamin A/C expression with siRNA results in the upregulation and mislocalization of MLIP, suggesting that MLIP localization to the nuclear envelope is dependent on the lamin proteins. It has been suggested that MLIP may function as a tethering protein linking LMNA to factors within the nuclear envelope of within PML bodies |
Immunogen | Immunogen: MLIP antibody was raised against a 16 amino acid synthetic peptide near the carboxy terminus of human MLIP. Buffer: MLIP Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [MLIP; C6orf142; C6orf142; Muscular LMNA-interacting protein; Muscular-enriched A-type laminin-interacting protein; muscular LMNA-interacting protein], [MLIP; MLIP; C6orf142; C6orf142] |
Gene, Accession # | [MLIP], Gene ID: 90523, NCBI: NP_612636, UniProt: Q5VWP3 |
Catalog # | MBS151524 |
Price | $375 |
Order / More Info | MLIP Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |